Leuprolide Acetate Injection is a prescription medication used to treat conditions such as endometriosis, uterine fibroids, precocious puberty, and prostate cancer. It is a synthetic hormone (gonadotropin releasing hormone agonist) that works by blocking the body's production of certain hormones that can lead to these conditions. This medication is given as an injection into a muscle or under the skin. Common side effects include hot flashes, mood swings, and headaches.